발간논문

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Vol.43, No.7, 481 ~ 488, 2005
Title
Evaluation of Cell Toxicity and Surface Properties of Surface Modified Ti and Ti Alloys
권오성 O. S. Kwon , 유재선 J. S. Yue , 박형호 H. H. Park , 이오연 O. Y. Lee , 이민호 M. H. Lee , 송기홍 K. H. Song
Abstract
This study was performed to investigate the surface properties and cell toxicity of the anodized and hydrothermally treated Ti, Ti-6Al-4V and Ti-6Al-7Nb alloys. Bioactivity was evaluated from surface activation layer formed on the surfaces in a Hanks` solution for 30 days. Cell toxicity was evaluated from optical density of survival cell. The porous oxide films were formed on all of Ti alloys by anodic oxidation. The anodic oxide films of Ti-6Al-7Nb alloy was composed of strong anatase peaks and weak rutile peaks and Ti was composed of strong anatase peaks without rutile peak and Ti-6Al-4V alloy was composed of weak anatase peaks and weak rutile peaks. The oxide films of all of specimens showed the increase in intensity of anatase peaks after hydrothermal treatment. The surface activity layers were formed only on the oxide films of Ti-6Al-7Nb alloy. Ti-6Al-7Nb alloy shown was significantly higher optical density than Ti and Ti-6Al-4V alloy on the MTT assay for cell toxicity evaluation.
Key Words
Bioactivity, Anodizing, Hydrothermal treatment, Cell toxicity, Ti Alloys
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